Scientific publication Rasmussen et al.

Scientific publication Rasmussen et al, Crystal structure of the beta-2 – adrenergic receptor-G protein complex, 2011 doi: 10.

Although the receptor beta 2AR was discovered 20 years ago, did the exact mechanism of its function is unknown, hampered improvements in drugs acting via this receptor. To explain the function of this receptor, it was important to the signaling complex, in fact, a dance catch in two parts with four main actors: the hormone , the receptor and the G protein, by by G-alpha – S, and G beta-gamma.Patients with depression bearing the abnormal gene also exhibit resistance to treatment by selective selective serotonin reuptake inhibitors , a class of drug the paroxetine After and fluoxetine that the team was. In addition to being diagnostic applications the genetic marker may therefore help in identification and pre those who patients who are likely to fail good at SSRIs therapy.